Two approaches are used to treat cluster headaches:
- Stopping an attack
- Preventing future attacks
To stop or at least control an attack in progress, you may be given high-dose oxygen therapy through a face mask for 15 to 20 minutes. Your doctor may also prescribe an injection of sumatriptan to ease the severe pain of a cluster headache. Sumatriptan is a selective serotonin receptor agonist. This medicine causes blood vessels in the brain to constrict. This eases pain. Other triptans may also be tried if sumatriptan doesn't help.
The second part of cluster headache treatment is to prevent recurrent attacks by using daily medicine. Several medicines are used to prevent cluster headache attacks:
- Verapamil. A medicine that relaxes blood vessels.
- Prednisone. A steroid that reduces inflammation and swelling.
- Lithium carbonate. A medicine that restores the balance of certain brain chemicals.
- Anti-seizure medicines. Medicines that may help reduce the number of cluster headaches.
- Galcanezumab. This is a newer medicine.